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SEC FORM 4 SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person^*

Three Arch Management IV, L.L.C.

(Last)

(First)

(Middle)

3200 ALPINE ROAD

(Street)

PORTOLA VALLEY

94028

(City)

(State)

(Zip)

2. Issuer Name and Ticker or Trading Symbol
ACELRX PHARMACEUTICALS INC [ ACRX ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

Director	X	10% Owner
Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
02/16/2011

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

	Form filed by One Reporting Person
X	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)		10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
Series C Convertible Preferred Stock	⁽⁷⁾	02/16/2011		C			24,878	⁽¹⁰⁾	⁽¹¹⁾	Common Stock	24,878	$0	0	I	See Footnote⁽⁴⁾
Warrant to purchase Series C Convertible Preferred Stock	⁽¹⁴⁾	02/16/2011		J		267⁽¹⁷⁾		⁽¹⁵⁾	⁽¹⁶⁾	Series C Preferred Stock	267	⁽¹⁷⁾	267	I	See Footnote⁽²⁾
Warrant to purchase Series C Convertible Preferred Stock	⁽¹⁴⁾	02/16/2011		X			267	⁽¹⁵⁾	⁽¹⁶⁾	Series C Preferred Stock	267	$0	0	I	See Footnote⁽²⁾
Series C Convertible Preferred Stock	⁽¹⁴⁾	02/16/2011		X		267		⁽¹⁰⁾	⁽¹¹⁾	Common Stock	267	$0	267	I	See Footnote⁽²⁾
Series C Convertible Preferred Stock	$5	02/16/2011		S			211⁽²³⁾	⁽¹⁰⁾	⁽¹¹⁾	Common Stock	211	$0	56	I	See Footnote⁽²⁾
Series C Convertible Preferred Stock	⁽⁷⁾	02/16/2011		C			56	⁽¹⁰⁾	⁽¹¹⁾	Common Stock	56	$0	0	I	See Footnote⁽²⁾
Warrant to purchase Series C Convertible Preferred Stock	⁽¹⁴⁾	02/16/2011		J		12,119⁽¹⁸⁾		⁽¹⁵⁾	⁽¹⁶⁾	Series C Preferred Stock	12,119	⁽¹⁸⁾	12,119	I	See Footnote⁽⁴⁾
Warrant to purchase Series C Convertible Preferred Stock	⁽¹⁴⁾	02/16/2011		X			12,119	⁽¹⁵⁾	⁽¹⁶⁾	Series C Preferred Stock	12,119	$0	0	I	See Footnote⁽⁴⁾
Series C Convertible Preferred Stock	⁽¹⁴⁾	02/16/2011		X		12,119		⁽¹⁰⁾	⁽¹¹⁾	Common Stock	12,119	$0	12,119	I	See Footnote⁽⁴⁾
Series C Convertible Preferred Stock	$5	02/16/2011		S			9,557⁽²⁴⁾	⁽¹⁰⁾	⁽¹¹⁾	Common Stock	9,557	$0	2,562	I	See Footnote⁽⁴⁾
Series C Convertible Preferred Stock	⁽⁷⁾	02/16/2011		C			2,562	⁽¹⁰⁾	⁽¹¹⁾	Common Stock	2,562	$0	0	I	See Footnote⁽⁴⁾
Convertible Promissory Note	⁽¹⁹⁾	02/16/2011		J		$4,220.08⁽¹⁷⁾		⁽¹⁹⁾	⁽¹⁹⁾	Common Stock	1,073	$0	1,073	I	See Footnote⁽²⁾
Convertible Promissory Note	⁽²⁰⁾	02/16/2011		J		$191,131.94⁽¹⁸⁾		⁽²⁰⁾	⁽²⁰⁾	Common Stock	48,605	$0	48,605	I	See Footnote⁽⁴⁾
Convertible Promissory Note	⁽¹⁹⁾	02/16/2011		C			$4,220.08	⁽¹⁹⁾	⁽¹⁹⁾	Common Stock	1,073	$0	0	I	See Footnote⁽²⁾
Convertible Promissory Note	⁽²⁰⁾	02/16/2011		C			$191,131.94	⁽²⁰⁾	⁽²⁰⁾	Common Stock	48,605	$0	0	I	See Footnote⁽⁴⁾

1. Name and Address of Reporting Person^*

Three Arch Management IV, L.L.C.

(Last)

(First)

(Middle)

3200 ALPINE ROAD

(Street)

PORTOLA VALLEY

94028

(City)

(State)

(Zip)

1. Name and Address of Reporting Person^*

THREE ARCH ASSOCIATES IV LP

(Last)

(First)

(Middle)

3200 ALPINE ROAD

(Street)

PORTOLA VALLEY

94028

(City)

(State)

(Zip)

1. Name and Address of Reporting Person^*

WAN MARK A

(Last)

(First)

(Middle)

C/O THREE ARCH PARTNERS

3200 ALPINE RD

(Street)

PORTOLA VALLEY

94028

(City)

(State)

(Zip)

1. Name and Address of Reporting Person^*

JAEGER WILFRED E

(Last)

(First)

(Middle)

C/O THREE ARCH PARTNERS

3200 ALPINE RD

(Street)

PORTOLA VALLEY

94028

(City)

(State)

(Zip)

1. Name and Address of Reporting Person^*

THREE ARCH PARTNERS IV LP

(Last)

(First)

(Middle)

(Street)

(City)

(State)

(Zip)

Explanation of Responses:

2. The shares are held by Three Arch Associates IV, L.P. The voting and dispositive decisions with respect to the shares held by Three Arch Associates IV, L.P., are made by the following Managing Members of its general partner Three Arch Management IV, L.L.C.: Mark Wan and Wilfred Jaeger, each of whom disclaims beneficial ownership of such shares.

4. The shares are held by Three Arch Partners IV, L.P. The voting and dispositive decisions with respect to the shares held by Three Arch Partners IV, L.P., are made by the following Managing Members of its general partner Three Arch Management IV, L.L.C.: Mark Wan and Wilfred Jaeger, each of whom disclaims beneficial ownership of such shares.

7. The shares reflect the automatic conversion of shares of the Issuer's Series C Convertible Preferred Stock into Common Stock on a one-for-one basis upon the closing of the Issuer's initial public offering.

10. Immediately convertible into shares of the Issuer's Common Stock.

11. These shares have no expiration date.

14. The exercise price is $3.942 per share.

15. Immediately exercisable prior to and contingent upon the closing of the Issuer's initial public offering.

16. Pursuant to its terms, the warrant was to be terminated at the closing of the Issuer's initial public offering. Holder elected to net exercise the warrants immediately prior to the closing of the Issuer's initial public offering. In the event the Issuer's public offering did not occur, the warrant would have terminated on September 14, 2017, unless earlier terminated in accordance with its terms, in a liquidation or change of control transaction.

17. Pursuant to that certain Note and Warrant Transfer Agreement dated February 16, 2011, ACP IV, L.P. transferred (i) a convertible promissory note in the amount of $4,292.76 including accrued interest and (ii) an associated warrant to purchase preferred stock of the Issuer, exercisable into 267 shares of Series C Convertible Preferred Stock to Three Arch Associates IV, L.P., for a nominal consideration, contingent upon the closing of the Issuer's initial public offering.

18. Pursuant to that certain Note and Warrant Transfer Agreement dated February 16, 2011, ACP IV, L.P. transferred (i) a convertible promissory note in the amount of $194,423.66 including accrued interest and (ii) an associated warrant to purchase preferred stock of the Issuer, exercisable into 12,119 shares of Series C Convertible Preferred Stock to Three Arch Partners IV, L.P., for a nominal consideration, contingent upon the closing of the Issuer's initial public offering.

19. A note with the principal amount plus accrued interest of $4,292.76 converted automatically upon the closing of the Issuer's initial public offering into shares of Common Stock at a conversion price of $4.00, which is 80.0% of the per share price of the Common Stock sold in the Issuer's initial public offering.

20. A note with the principal amount plus interest of $194,423.66 converted automatically upon the closing of the Issuer's initial public offering into shares of Common Stock at a conversion price of $4.00, which is 80.0% of the per share price of the Common Stock sold in the Issuer's initial public offering.

23. These shares represent the net exercise of a warrant to purchase Series C Convertible Preferred Stock for an acquisition of 56 shares of Series C Convertible Preferred Stock of the Issuer.

24. These shares represent the net exercise of a warrant to purchase Series C Convertible Preferred Stock for an acquisition of 2,562 shares of Series C Convertible Preferred Stock of the Issuer.

Remarks:

Form 2 of 2

	/s/ Stephen J. Bonelli, Attorney-in-fact	02/18/2011
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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