000 - Document - Document And Entity Information link:calculationLink link:definitionLink link:presentationLink 001 - Statement - Condensed Consolidated Balance Sheets (Current Period Unaudited) link:calculationLink link:definitionLink link:presentationLink 002 - Statement - Condensed Consolidated Balance Sheets (Current Period Unaudited) (Parentheticals) link:calculationLink link:definitionLink link:presentationLink 003 - Statement - Condensed Consolidated Statements of Comprehensive Loss (Unaudited) link:calculationLink link:definitionLink link:presentationLink 004 - Statement - Condensed Consolidated Statements of Cash Flows (Unaudited) link:calculationLink link:definitionLink link:presentationLink 005 - Disclosure - Note 1 - Organization and Summary of Significant Accounting Policies link:calculationLink link:definitionLink link:presentationLink 006 - Disclosure - Note 2 - Investments and Fair Value Measurement link:calculationLink link:definitionLink link:presentationLink 007 - Disclosure - Note 3 - Inventories link:calculationLink link:definitionLink link:presentationLink 008 - Disclosure - Note 4 - U.S. Department of Defense Contract link:calculationLink link:definitionLink link:presentationLink 009 - Disclosure - Note 5 - Collaboration Agreement link:calculationLink link:definitionLink link:presentationLink 010 - Disclosure - Note 6 - Long-term Debt link:calculationLink link:definitionLink link:presentationLink 011 - Disclosure - Note 7 - Liability Related to Sale of Future Royalties link:calculationLink link:definitionLink link:presentationLink 012 - Disclosure - Note 8 - Warrants link:calculationLink link:definitionLink link:presentationLink 013 - Disclosure - Note 9 - Stock-based Compensation link:calculationLink link:definitionLink link:presentationLink 014 - Document - Note 10 - Net Loss Per Share of Common Stock link:calculationLink link:definitionLink link:presentationLink 015 - Disclosure - Significant Accounting Policies (Policies) link:calculationLink link:definitionLink link:presentationLink 016 - Disclosure - Note 2 - Investments and Fair Value Measurement (Tables) link:calculationLink link:definitionLink link:presentationLink 017 - Disclosure - Note 3 - Inventories (Tables) link:calculationLink link:definitionLink link:presentationLink 018 - Disclosure - Note 5 - Collaboration Agreement (Tables) link:calculationLink link:definitionLink link:presentationLink 019 - Disclosure - Note 7 - Liability Related to Sale of Future Royalties (Tables) link:calculationLink link:definitionLink link:presentationLink 020 - Disclosure - Note 9 - Stock-based Compensation (Tables) link:calculationLink link:definitionLink link:presentationLink 021 - Disclosure - Note 10 - Net Loss Per Share of Common Stock (Tables) link:calculationLink link:definitionLink link:presentationLink 022 - Disclosure - Note 2 - Investments and Fair Value Measurement (Details Textual) link:calculationLink link:definitionLink link:presentationLink 023 - Disclosure - Note 2 - Investments and Fair Value Measurement - Summary of Cash, Cash Equivalents and Investments (Details) link:calculationLink link:definitionLink link:presentationLink 024 - Disclosure - Note 2 - Investments and Fair Value Measurement - Fair Value of Financial Assets and Liabilities by Level Within Fair Value Hierarchy (Details) link:calculationLink link:definitionLink link:presentationLink 025 - Disclosure - Note 2 - Investments and Fair Value Measurement - Assumptions Used in Black-Scholes Option Pricing Model to Estimate Fair Value of Pipe Warrants (Details) link:calculationLink link:definitionLink link:presentationLink 026 - Disclosure - Note 2 - Investments and Fair Value Measurement - Summary of Changes in Fair Value of Level III Financial Liabilities (Details) link:calculationLink link:definitionLink link:presentationLink 027 - Disclosure - Note 3 - Inventories - Inventory Components (Details) link:calculationLink link:definitionLink link:presentationLink 028 - Disclosure - Note 4 - U.S. Department of Defense Contract (Details Textual) link:calculationLink link:definitionLink link:presentationLink 029 - Disclosure - Note 5 - Collaboration Agreement (Details Textual) link:calculationLink link:definitionLink link:presentationLink 030 - Disclosure - Note 5 - Collaboration Agreement - A Summary of Revenue Recognized Under the Amended Agreements (Details) link:calculationLink link:definitionLink link:presentationLink 031 - Disclosure - Note 6 - Long-term Debt (Details Textual) link:calculationLink link:definitionLink link:presentationLink 032 - Disclosure - Note 7 - Liability Related to Sale of Future Royalties (Details Textual) link:calculationLink link:definitionLink link:presentationLink 033 - Disclosure - Note 7 - Liability Related to Sale of Future Royalties - Activity of Liability Related to Sale of Future Royalties (Details) link:calculationLink link:definitionLink link:presentationLink 034 - Disclosure - Note 8 - Warrants (Details Textual) link:calculationLink link:definitionLink link:presentationLink 035 - Disclosure - Note 9 - Stock-based Compensation (Details Textual) link:calculationLink link:definitionLink link:presentationLink 036 - Disclosure - Note 9 - Stock-based Compensation - Stock-based Compensation Expense (Details) link:calculationLink link:definitionLink link:presentationLink 037 - Disclosure - Note 10 - Net Loss Per Share of Common Stock - Computation of Basic and Diluted Net Loss Per Share of Common (Details) link:calculationLink link:definitionLink link:presentationLink 038 - Disclosure - Note 10 - Net Loss Per Share of Common Stock - Outstanding Shares of Common Stock Equivalents Excluded From Computation of Diluted Net Loss Per Share (Details) link:calculationLink link:definitionLink link:presentationLink